Skin biopsy Belgrade

Skin biopsy

Discovering the causes of unusual skin changes, establishing an accurate diagnosis, and timely detection of benign or malignant lesions are most reliably performed through dermatological procedures, which include skin biopsy. This routine and minimally invasive medical procedure involves taking a small tissue sample from a suspicious spot on the skin, which is then sent for histopathological analysis under a microscope. A biopsy is a key diagnostic step for chronic rashes, autoimmune diseases, unclear infections, as well as for altered moles and suspected skin cancers.

If you need diagnostic services, dermoscopy, and expert skin biopsies, on this page you can find a list of dermatological offices and clinics in Belgrade.

Most Common Methods of Tissue Sampling

Depending on the depth, size, and nature of the skin lesion, several basic biopsy techniques are applied.

Punch biopsy is performed using a special circular instrument resembling a small stamp that takes a cylindrical sample of all skin layers (epidermis, dermis, and the upper layer of subcutaneous fat tissue). Shave biopsy is used for superficial lesions where only the top layer of the skin is removed using a sterile surgical blade or scalpel, without the need for stitches. Excisional biopsy involves the complete removal of the entire lesion along with a protective margin of healthy tissue, which is the gold standard when moles and melanoma are suspected. For extensive lesions, an incisional biopsy is applied, where only a representative part of the lesion is taken.

Preparation, Recovery, and Histopathological Report

The procedure is performed in an outpatient setting with the maximum application of all aseptic measures.

After injecting a local anesthetic, the dermatologist or surgeon takes the sample, places one or two stitches if necessary, and dresses the area with sterile gauze. The sampling site heals quickly, and the resulting scar is minimal and fades over time. The tissue sample is immersed in a formalin solution and sent to the pathologist, who issues an official histopathological report after special staining and microscopic examination.

How to Care for the Wound After a Skin Biopsy?

After the biopsy is completed, it is extremely important to properly care for the puncture or suture site to prevent infections and ensure proper healing. Leave the sterile bandage or adhesive plaster dry on the wound for the first 24 to 48 hours, after which you can gently wash the wound with water and mild soap, pat it dry, and apply the recommended antibiotic or regenerative cream. Avoid submerging the wound in pools, saunas, or hot tubs until the stitches are removed or the wound is completely healed. If stitches were placed, they will be removed after 7 to 14 days, depending on whether the biopsy was performed on the face, torso, or limbs.